EIF4G1 Polyclonal Antibody | G-AB-11748

EIF4G1 Polyclonal Antibody | G-AB-11748 | Gentaur Antibodies

Overview: The protein encoded by this gene is a component of the multi-subunit protein complex EIF4F. This complex facilitates the recruitment of mRNA to the ribosome, which is a rate-limiting step during the initiation phase of protein synthesis. The recognition of the mRNA cap and the ATP-dependent unwinding of 5'-terminal secondary structure is catalyzed by factors in this complex. The subunit encoded by this gene is a large scaffolding protein that contains binding sites for other members of the EIF4F complex. A domain at its N-terminus can also interact with the poly (A) -binding protein, which may mediate the circularization of mRNA during translation. Alternative splicing results in multiple transcript variants, some of which are derived from alternative promoter usage.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Epigenetics and Nuclear Signaling

Synonyms: EIF4G1, EIF-4G1, EIF4F, EIF4G, EIF4GI, P220, PARK18

Reactivity: Human

Host: Rabbit

Isotype: IgG

Gene ID: 1981

Accession #:

Clonality:

Immunogen: A synthetic peptide of human EIF4G1 (NP_886553.3) .

Clone #:

Conjugation: Unconjugated

Swissprot: Q04637

Santa Cruz:

Calculated MW:

Observed MW:

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: IHC, IF

Dilution: IHC 1:50-1:200 IF 1:50-1:200

Storage: Store at -20°C. Avoid freeze / thaw cycles.

EIF4G1 Polyclonal Antibody DataSheet