ELF3 Polyclonal Antibody | G-AB-11050

ELF3 Polyclonal Antibody | G-AB-11050 | Gentaur Antibodies

Overview: Transcriptional activator that binds and transactivates ETS sequences containing the consensus nucleotide core sequence GGA[AT]. Acts synergistically with POU2F3 to transactivate the SPRR2A promoter and with RUNX1 to transactivate the ANGPT1 promoter. Also transactivates collagenase, CCL20, CLND7, FLG, KRT8, NOS2, PTGS2, SPRR2B, TGFBR2 and TGM3 promoters. Represses KRT4 promoter activity. Involved in mediating vascular inflammation. May play an important role in epithelial cell differentiation and tumorigenesis. May be a critical downstream effector of the ERBB2 signaling pathway. May be associated with mammary gland development and involution. Plays an important role in the regulation of transcription with TATA-less promoters in preimplantation embryos, which is essential in preimplantation development (By similarity) .

Category Type: Polyclonal Antibody

Research Areas: Cancer, Epigenetics and Nuclear Signaling

Synonyms: ELF3, EPR-1, ERT, ESE-1, ESX

Reactivity: Human, Rat

Host: Rabbit

Isotype: IgG

Gene ID: 1999

Accession #:

Clonality:

Immunogen: Recombinant fusion protein of human ELF3 (NP_004424.3) .

Clone #:

Conjugation: Unconjugated

Swissprot: P78545

Santa Cruz:

Calculated MW:

Observed MW:

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: IHC, IF

Dilution: IHC 1:50-1:200 IF 1:10-1:100

Storage: Store at -20°C. Avoid freeze / thaw cycles.

ELF3 Polyclonal Antibody DataSheet