Epigenetics & Nuclear Signaling Antibody

TRIM37 Polyclonal Antibody | G-AB-00198 | Gentaur AntibodiesOverview: This gene encodes a member of the tripartite motif (TRIM) family, whose members are involved in diverse cellular functions such as developmental patterning and oncogenesis. The TRIM...

MEF2C Polyclonal Antibody | G-AB-00196 | Gentaur AntibodiesOverview: This locus encodes a member of the MADS box transcription enhancer factor 2 (MEF2) family of proteins, which play a role in myogenesis. The encoded protein, MEF2 polypeptide C, has both...

CDC46 Polyclonal Antibody | G-AB-00194 | Gentaur AntibodiesOverview: The protein encoded by this gene is structurally very similar to the CDC46 protein from S. cerevisiae, a protein involved in the initiation of DNA replication. The encoded protein is a...

MCM7 Polyclonal Antibody | G-AB-00191 | Gentaur AntibodiesOverview: The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The...

MCM3 Polyclonal Antibody | G-AB-00190 | Gentaur AntibodiesOverview: The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The...

S100B Polyclonal Antibody | G-AB-00185 | Gentaur AntibodiesOverview: The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a...

HOXA1 Polyclonal Antibody | G-AB-00184 | Gentaur AntibodiesOverview: In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these...

EEF2 Polyclonal Antibody | G-AB-00179 | Gentaur AntibodiesOverview: This gene encodes a member of the GTP-binding translation elongation factor family. This protein is an essential factor for protein synthesis. It promotes the GTP-dependent translocation...

NR1H3 Polyclonal Antibody | G-AB-00178 | Gentaur AntibodiesOverview: The protein encoded by this gene belongs to the NR1 subfamily of the nuclear receptor superfamily. The NR1 family members are key regulators of macrophage function, controlling...

SF3B3 Polyclonal Antibody | G-AB-00173 | Gentaur AntibodiesOverview: This gene encodes subunit 3 of the splicing factor 3b protein complex. Splicing factor 3b, together with splicing factor 3a and a 12S RNA unit, forms the U2 small nuclear...

IMP3 Polyclonal Antibody | G-AB-00171 | Gentaur AntibodiesOverview: This gene encodes the human homolog of the yeast Imp3 protein. The protein localizes to the nucleoli and interacts with the U3 snoRNP complex. The protein contains an S4 domain. IMP3...

HMGB2 Polyclonal Antibody | G-AB-00162 | Gentaur AntibodiesOverview: This gene encodes a member of the non-histone chromosomal high mobility group protein family. The proteins of this family are chromatin-associated and ubiquitously distributed in the...

C15orf23 Polyclonal Antibody | G-AB-00156 | Gentaur AntibodiesOverview: Essential component of the mitotic spindle required for faithful chromosome segregation and progression into anaphase . Promotes the metaphase-to-anaphase transition and is required...

SF3A3 Polyclonal Antibody | G-AB-00154 | Gentaur AntibodiesOverview: This gene encodes subunit 3 of the splicing factor 3a protein complex. The splicing factor 3a heterotrimer includes subunits 1, 2 and 3 and is necessary for the in vitro conversion of...

EIF5A2 Polyclonal Antibody | G-AB-00151 | Gentaur AntibodiesOverview: EIF5A2 (Eukaryotic Translation Initiation Factor 5A2) is a Protein Coding gene. Among its related pathways areGamma carboxylation, hypusine formation and arylsulfatase...

SIX2 Polyclonal Antibody | G-AB-00150 | Gentaur AntibodiesOverview: This gene is a member of the vertebrate gene family which encode proteins homologous to the Drosophila 'sine oculis' homeobox protein. The encoded protein is a transcription factor...

THRAP3 Polyclonal Antibody | G-AB-00148 | Gentaur AntibodiesOverview: THRAP3 (Thyroid Hormone Receptor Associated Protein 3) is a Protein Coding gene. Among its related pathways arePEDF Induced SignalingandCircadian rythm related genes. GO annotations...

SIX1 Polyclonal Antibody | G-AB-00146 | Gentaur AntibodiesOverview: The protein encoded by this gene is a homeobox protein that is similar to the Drosophila 'sine oculis' gene product. This gene is found in a cluster of related genes on chromosome 14 and...

EGR2 Polyclonal Antibody | G-AB-00137 | Gentaur AntibodiesOverview: The protein encoded by this gene is a transcription factor with three tandem C2H2-type zinc fingers. Defects in this gene are associated with Charcot-Marie-Tooth disease type 1D (CMT1D)...

STAT2 Polyclonal Antibody | G-AB-00131 | Gentaur AntibodiesOverview: Signal transducer and activator of transcription that mediates signaling by type I IFNs (IFN-alpha and IFN-beta) . Following type I IFN binding to cell surface receptors, Jak kinases...

BAP1 Polyclonal Antibody | G-AB-00129 | Gentaur AntibodiesOverview: Deubiquitinating enzyme that plays a key role in chromatin by mediating deubiquitination of histone H2A and HCFC1. Catalytic component of the PR-DUB complex, a complex that specifically...

P73 Polyclonal Antibody | G-AB-00126 | Gentaur AntibodiesOverview: Participates in the apoptotic response to DNA damage. Isoforms containing the transactivation domain are pro-apoptotic, isoforms lacking the domain are anti-apoptotic and block the...

IGF2BP2 Polyclonal Antibody | G-AB-00117 | Gentaur AntibodiesOverview: RNA-binding factor that recruits target transcripts to cytoplasmic protein-RNA complexes (mRNPs) . This transcript 'caging' into mRNPs allows mRNA transport and transient storage. It...

IkB alpha Polyclonal Antibody | G-AB-00111 | Gentaur AntibodiesOverview: Inhibits the activity of dimeric NF-kappa-B/REL complexes by trapping REL dimers in the cytoplasm through masking of their nuclear localization signals. On cellular stimulation by...

SOX-2 Polyclonal Antibody | G-AB-00100 | Gentaur AntibodiesOverview: Sox2, also known as SRY (sex determining region Y) -box 2, is a transcription factor essential for maintaining self-renewal of undifferentiated ES cells and is one of the key...

RPS25 Polyclonal Antibody | G-AB-00088 | Gentaur AntibodiesOverview: ibosomal protein S25 (RPS25) is a novel MDM2 interacting protein. It may be involved in viral replication of Dicistroviridae and hepatitis C viruses. RPS25 is overexpressed in human...

KRAS Polyclonal Antibody | G-AB-00085 | Gentaur AntibodiesOverview: KRAS, also called p21, is a member of the Ras superfamily of proteins. It is located on human chromosome 12, and contains four coding exons and a 5' non-coding exon (PMID: 12778136) ...

TUFM Polyclonal Antibody | G-AB-00080 | Gentaur AntibodiesOverview: TUFM, also named as Elongation factor Tu, mitochondrial, is a 452 amino acid protein, which contains 1 tr-type G (guanine nucleotide-binding) domain and belongs to the TRAFAC class...

TRIP4 Polyclonal Antibody | G-AB-00075 | Gentaur AntibodiesOverview: This gene encodes a subunit of the tetrameric nuclear activating signal cointegrator 1 (ASC-1) complex, which associates with transcriptional coactivators, nuclear receptors and basal...

STK4 Polyclonal Antibody | G-AB-00073 | Gentaur AntibodiesOverview: The protein encoded by this gene is a cytoplasmic kinase that is structurally similar to the yeast Ste20p kinase, which acts upstream of the stress-induced mitogen-activated protein...

MGMT Polyclonal Antibody | G-AB-00072 | Gentaur AntibodiesOverview: Alkylating agents are potent carcinogens that can result in cell death, mutation and cancer. The protein encoded by this gene is a DNA repair protein that is involved in cellular defense...

IRF3 Polyclonal Antibody | G-AB-00071 | Gentaur AntibodiesOverview: This gene encodes a member of the interferon regulatory transcription factor (IRF) family. The encoded protein is found in an inactive cytoplasmic form that upon serine/threonine...

CDC40 Polyclonal Antibody | G-AB-00067 | Gentaur AntibodiesOverview: Associates with the spliceosome late in the splicing pathway and may function in the second step of pre-mRNA splicing.Category Type: Polyclonal AntibodyResearch Areas: Cancer, Cell...

ILF2 Polyclonal Antibody | G-AB-00066 | Gentaur AntibodiesOverview: Appears to function predominantly as a heterodimeric complex with ILF3. This complex may regulate transcription of the IL2 gene during T-cell activation. It can also promote the...

STAT3 Polyclonal Antibody | G-AB-00065 | Gentaur AntibodiesOverview: Signal transducer and transcription activator that mediates cellular responses to interleukins, KITLG/SCF, LEP and other growth factors. Once activated, recruits coactivators, such as...

PARP3 Polyclonal Antibody | G-AB-00062 | Gentaur AntibodiesOverview: Involved in the base excision repair (BER) pathway, by catalyzing the poly (ADP-ribosyl) ation of a limited number of acceptor proteins involved in chromatin architecture and in DNA...

P21 Polyclonal Antibody | G-AB-00054 | Gentaur AntibodiesOverview: May be involved in p53/TP53 mediated inhibition of cellular proliferation in response to DNA damage. Binds to and inhibits cyclin-dependent kinase activity, preventing phosphorylation of...

CDK2 Polyclonal Antibody | G-AB-00053 | Gentaur AntibodiesOverview: Serine/threonine-protein kinase involved in the control of the cell cycle; essential for meiosis, but dispensable for mitosis.Category Type: Polyclonal AntibodyResearch Areas: Cancer,...

CDK1 Polyclonal Antibody | G-AB-00045 | Gentaur AntibodiesOverview: CDK1, also named as CDC2, belongs to the protein kinase superfamily, CMGC Ser/Thr protein kinase family and CDC2/CDKX subfamily.CDC2 plays a key role in the control of the eukaryotic...

PPARA Polyclonal Antibody | G-AB-00044 | Gentaur AntibodiesOverview: Peroxisome proliferator-activated receptor alpha (PPARA) is a ligand-activated transcription factor that belongs to the PPAR nuclear receptor superfamily. PPARA is essential in the...

PBK Polyclonal Antibody | G-AB-00041 | Gentaur AntibodiesOverview: PBK (PDZ-binding kinase) is also named as TOPK, CT84, Nori-3, SPK and belongs to the MAP kinase kinase subfamily. PBK may have a role in the regulation of cellular proliferation and...

ENO1 Polyclonal Antibody | G-AB-00040 | Gentaur AntibodiesOverview: Enolase is an important glycolytic enzyme involved in the interconversion of 2-phosphoglycerate to phosphoenolpyruvate.Enolase were down-regulated in oxLDL-treated cells or in...

PCNA Polyclonal Antibody | G-AB-00038 | Gentaur AntibodiesOverview: This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation...

STAT1 Polyclonal Antibody | G-AB-00035 | Gentaur AntibodiesOverview: Signal transducer and activator of transcription that mediates signaling by interferons (IFNs) . Following type I IFN (IFN-alpha and IFN-beta) binding to cell surface receptors, Jak...

SMAD3 Polyclonal Antibody | G-AB-00034 | Gentaur AntibodiesOverview: Receptor-regulated SMAD (R-SMAD) that is an intracellular signal transducer and transcriptional modulator activated by TGF-beta (transforming growth factor) and activin type 1 receptor...

RELB Polyclonal Antibody | G-AB-00029 | Gentaur AntibodiesOverview: RELB, also named as Transcription factor RelB, is a 579 amino acid protein, which contains one RHD domain.RELB localizes in the nucleus and cytoplasm. RELB is a pleiotropic transcription...

ERG Polyclonal Antibody | G-AB-00027 | Gentaur AntibodiesOverview: Transcriptional regulator. May participate in transcriptional regulation through the recruitment of SETDB1 histone methyltransferase and subsequent modification of local chromatin...

S100B Polyclonal Antibody | G-AB-00023 | Gentaur AntibodiesOverview: S100B is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs and has been implicated in the regulation of cellular activities such as metabolism,...

AKT1 Polyclonal Antibody | G-AB-00022 | Gentaur AntibodiesOverview: The serine-threonine protein kinase AKT1 is catalytically inactive in serum-starved primary and immortalized fibroblasts. AKT1 and the related AKT2 are activated by platelet-derived...

Metallothionein Polyclonal Antibody | G-AB-00019 | Gentaur AntibodiesOverview: Metallothioneins have a high content of cysteine residues that bind various heavy metals; these proteins are transcriptionally regulated by both heavy metals and...

CRP Polyclonal Antibody | G-AB-00003 | Gentaur AntibodiesOverview: Displays several functions associated with host defense: it promotes agglutination, bacterial capsular swelling, phagocytosis and complement fixation through its calcium-dependent binding...