S100B Polyclonal Antibody | G-AB-00023
- 3 to 5 Working Days
- Human, Mouse, Rat
S100B Polyclonal Antibody | G-AB-00023 | Gentaur Antibodies
Overview: S100B is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs and has been implicated in the regulation of cellular activities such as metabolism, motility and proliferation. In the nervous system, S100B is constitutively released by astrocytes into the extracellular space and at nanomolar concentrations, it can promote neurite outgrowth and protect neurons against oxidative stress. Within the central nervous system (CNS) , S100B is thought to be a marker for astroglial activation, linking astrocyte dysfunction to schizophrenia. In addition to astrocytes, S100B is released from many cell types, such as, adipocytes, chondrocytes, cardiomyocytes and lymphocytes. Serum S100B represents a new bomarker for mood disorders.
Category Type: Polyclonal Antibody
Research Areas: Cancer, Cell Biology, Epigenetics and Nuclear Signaling, Stem cells
Synonyms: NEF, Protein S100 B, Protein S100-B, S 100 calcium binding protein beta chain, S 100 protein beta chain, S-100 protein beta chain, S-100 protein subunit beta, S100, S100 calcium binding protein beta (neural) , S100 calcium-binding protein B, S100 protein beta chain, S100B, S100B, S100beta
Reactivity: Human, Mouse, Rat
Accession #: NP_006263
Immunogen: Recombinant Human S100B protein
Concentration: 2 mg/mL
Buffer: PBS with 0.02% sodium azide and 50% glycerol pH 7.4.
Purification method: Affinity purification
Dilution: IHC 1:50-1:100
Storage: Store at -20°C. Avoid freeze / thaw cycles.