EXOC2 Polyclonal Antibody | G-AB-12104
Gentaur Antibodies
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Gentaur Antibodies
EXOC2 Polyclonal Antibody | G-AB-12104
- SKU:
- G-AB-12104
- Availability:
- 3 to 5 Working Days
- Host:
- Rabbit
- Reactivity:
- Human, Mouse, Rat
EXOC2 Polyclonal Antibody | G-AB-12104 | Gentaur Antibodies
Overview: The protein encoded by this gene is a component of the exocyst complex, a multi-protein complex essential for the polarized targeting of exocytic vesicles to specific docking sites on the plasma membrane. Though best characterized in yeast, the component proteins and the functions of the exocyst complex have been demonstrated to be highly conserved in higher eukaryotes. At least eight components of the exocyst complex, including this protein, are found to interact with the actin cytoskeletal remodeling and vesicle transport machinery. This interaction has been shown to mediate filopodia formation in fibroblasts. This protein has been shown to interact with the Ral subfamily of GTPases and thereby mediate exocytosis by tethering vesicles to the plasma membrane. Alternative splicing results in multiple transcript variants.
Category Type: Polyclonal Antibody
Research Areas: Signal Transduction
Synonyms: EXOC2, SEC5, SEC5L1, Sec5p
Reactivity: Human, Mouse, Rat
Host: Rabbit
Isotype: IgG
Gene ID: 55770
Accession #:
Clonality:
Immunogen: Recombinant fusion protein of human EXOC2 (NP_060773.3) .
Clone #:
Conjugation: Unconjugated
Swissprot: Q96KP1
Santa Cruz:
Calculated MW: 104 kDa
Observed MW: 108 kDa
Concentration: 1 mg/mL
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Purification method: Affinity purification
Application: WB, IF
Dilution: WB 1:500-1:2000 IF 1:50-1:200
Storage: Store at -20°C. Avoid freeze / thaw cycles.
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