F11R Polyclonal Antibody | G-AB-07793

F11R Polyclonal Antibody | G-AB-07793 | Gentaur Antibodies

Overview: Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. The protein encoded by this immunoglobulin superfamily gene member is an important regulator of tight junction assembly in epithelia. In addition, the encoded protein can act as (1) a receptor for reovirus, (2) a ligand for the integrin LFA1, involved in leukocyte transmigration, and (3) a platelet receptor. Multiple 5' alternatively spliced variants, encoding the same protein, have been identified but their biological validity has not been established.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Cardiovascular, Signal Transduction

Synonyms: F11R, CD321, JAM, JAM1, JAMA, JCAM, KAT, PAM-1

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID: 50848

Accession #:

Clonality:

Immunogen: Recombinant fusion protein of human F11R (NP_058642.1) .

Clone #:

Conjugation: Unconjugated

Swissprot: Q9Y624

Santa Cruz:

Calculated MW: 27 kDa/32 kDa

Observed MW: 40 kDa

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: WB, IF

Dilution: WB 1:500-1:2000 IF 1:50-1:200

Storage: Store at -20°C. Avoid freeze / thaw cycles.

F11R Polyclonal Antibody DataSheet