Factor IX / F9 Polyclonal Antibody | G-AB-09186
Gentaur Antibodies
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Gentaur Antibodies
Factor IX / F9 Polyclonal Antibody | G-AB-09186
- SKU:
- G-AB-09186
- Availability:
- 3 to 5 Working Days
- Host:
- Rabbit
- Reactivity:
- Human, Mouse, Rat
Factor IX / F9 Polyclonal Antibody | G-AB-09186 | Gentaur Antibodies
Overview: This gene encodes vitamin K-dependent coagulation factor IX that circulates in the blood as an inactive zymogen. This factor is converted to an active form by factor XIa, which excises the activation peptide and thus generates a heavy chain and a light chain held together by one or more disulfide bonds. The role of this activated factor IX in the blood coagulation cascade is to activate factor X to its active form through interactions with Ca+2 ions, membrane phospholipids, and factor VIII. Alterations of this gene, including point mutations, insertions and deletions, cause factor IX deficiency, which is a recessive X-linked disorder, also called hemophilia B or Christmas disease. Alternative splicing results in multiple transcript variants encoding different isoforms that may undergo similar proteolytic processing.
Category Type: Polyclonal Antibody
Research Areas: Cardiovascular, Immunology
Synonyms: F9, F9 p22, FIX, HEMB, P19, PTC, THPH8, F9p22
Reactivity: Human, Mouse, Rat
Host: Rabbit
Isotype: IgG
Gene ID: 2158
Accession #:
Clonality:
Immunogen: Recombinant fusion protein of human Factor IX / F9 (NP_000124.1) .
Clone #:
Conjugation: Unconjugated
Swissprot: P00740
Santa Cruz:
Calculated MW: 47 kDa/51 kDa
Observed MW: 50 kDa
Concentration: 1 mg/mL
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Purification method: Affinity purification
Application: WB, IF
Dilution: WB 1:500-1:2000 IF 1:50-1:200
Storage: Store at -20°C. Avoid freeze / thaw cycles.
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