Factor IX / F9 Polyclonal Antibody | G-AB-09186

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$156.96 - $334.80
SKU:
G-AB-09186
Availability:
3 to 5 Working Days
Host:
Rabbit
Reactivity:
Human, Mouse, Rat
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Factor IX / F9 Polyclonal Antibody | G-AB-09186 | Gentaur Antibodies

Overview: This gene encodes vitamin K-dependent coagulation factor IX that circulates in the blood as an inactive zymogen. This factor is converted to an active form by factor XIa, which excises the activation peptide and thus generates a heavy chain and a light chain held together by one or more disulfide bonds. The role of this activated factor IX in the blood coagulation cascade is to activate factor X to its active form through interactions with Ca+2 ions, membrane phospholipids, and factor VIII. Alterations of this gene, including point mutations, insertions and deletions, cause factor IX deficiency, which is a recessive X-linked disorder, also called hemophilia B or Christmas disease. Alternative splicing results in multiple transcript variants encoding different isoforms that may undergo similar proteolytic processing.

Category Type: Polyclonal Antibody

Research Areas: Cardiovascular, Immunology

Synonyms: F9, F9 p22, FIX, HEMB, P19, PTC, THPH8, F9p22

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID: 2158

Accession #:

Clonality:

Immunogen: Recombinant fusion protein of human Factor IX / F9 (NP_000124.1) .

Clone #:

Conjugation: Unconjugated

Swissprot: P00740

Santa Cruz:

Calculated MW: 47 kDa/51 kDa

Observed MW: 50 kDa

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: WB, IF

Dilution: WB 1:500-1:2000 IF 1:50-1:200

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Factor IX / F9 Polyclonal Antibody DataSheet

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