FBXW5 Polyclonal Antibody | G-AB-12359
- 3 to 5 Working Days
FBXW5 Polyclonal Antibody | G-AB-12359 | Gentaur Antibodies
Overview: This gene encodes a member of the F-box protein family, members of which are characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box) , which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into three classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene contains WD-40 domains, in addition to an F-box motif, so it belongs to the Fbw class. Alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene, however, they were found to be nonsense-mediated mRNA decay (NMD) candidates, hence not represented.
Category Type: Polyclonal Antibody
Synonyms: FBXW5, Fbw5
Gene ID: 54461
Immunogen: Recombinant fusion protein of human FBXW5 (NP_061871.1) .
Calculated MW: 42 kDa/63 kDa
Observed MW: 72 kDa
Concentration: 1 mg/mL
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Purification method: Affinity purification
Dilution: WB 1:200-1:1000
Storage: Store at -20°C. Avoid freeze / thaw cycles.