Fibulin 5 Polyclonal Antibody | G-AB-01276

Fibulin 5 Polyclonal Antibody | G-AB-01276 | Gentaur Antibodies

Overview: The protein encoded by this gene is a secreted, extracellular matrix protein containing an Arg-Gly-Asp (RGD) motif and calcium-binding EGF-like domains. It promotes adhesion of endothelial cells through interaction of integrins and the RGD motif. It is prominently expressed in developing arteries but less so in adult vessels. However, its expression is reinduced in balloon-injured vessels and atherosclerotic lesions, notably in intimal vascular smooth muscle cells and endothelial cells. Therefore, the protein encoded by this gene may play a role in vascular development and remodeling. Defects in this gene are a cause of autosomal dominant cutis laxa, autosomal recessive cutis laxa type I (CL type I) , and age-related macular degeneration type 3 (ARMD3) .

Category Type: Polyclonal Antibody

Research Areas: Cardiovascular, Signal Transduction

Synonyms: ADCL2, ARCL1A, ARMD3, Dance, Developmental arteries and neural crest EGF like protein, Developmental arteries and neural crest EGF-like protein, EVEC, Fbln5, FBLN5, FIBL 5, FIBL-5, Fibulin-5, FLJ90059, UP50, Urine p50 protein

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID:

Accession #: NP_006320

Clonality: Polyclonal

Immunogen: Synthetic peptide of human FBLN5

Clone #:

Conjugation: Unconjugated

Swissprot: Q9UBX5

Santa Cruz: sc-23062/sc-30170

Calculated MW:

Observed MW:

Concentration: 1.2 mg/mL

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification method: Affinity purification

Application: IHC, ELISA

Dilution: IHC 1:50-1:200

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Fibulin 5 Polyclonal Antibody DataSheet