FLNA Polyclonal Antibody | G-AB-02493

FLNA Polyclonal Antibody | G-AB-02493 | Gentaur Antibodies

Overview: The protein encoded by this gene is an actin-binding protein that crosslinks actin filaments and links actin filaments to membrane glycoproteins. The encoded protein is involved in remodeling the cytoskeleton to effect changes in cell shape and migration. This protein interacts with integrins, transmembrane receptor complexes, and second messengers. Defects in this gene are a cause of several syndromes, including periventricular nodular heterotopias (PVNH1, PVNH4) , otopalatodigital syndromes (OPD1, OPD2) , frontometaphyseal dysplasia (FMD) , Melnick-Needles syndrome (MNS) , and X-linked congenital idiopathic intestinal pseudoobstruction (CIIPX) . Two transcript variants encoding different isoforms have been found for this gene.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Signal Transduction

Synonyms: ABP 280, ABP-280, Actin-binding protein 280, Alpha filamin, Alpha-filamin, APBX, CSBS, CVD1, Endothelial actin binding protein, Endothelial actin-binding protein, Filamin 1, Filamin A alpha, Filamin A, Filamin-1, Filamin-A, FLN, FLN-A, FLN1, FLNA, FLNA, FMD, MNS, NHBP, Non muscle filamin, Non-muscle filamin, OPD, OPD1, OPD2, XLVD, XMVD

Reactivity: Human, Mouse

Host: Rabbit

Isotype: IgG

Gene ID:

Accession #: NP_001104026

Clonality: Polyclonal

Immunogen: Recombinant protein of human FLNA

Clone #:

Conjugation: Unconjugated

Swissprot: P21333

Santa Cruz: sc-7565/sc-28284

Calculated MW: 281 kDa

Observed MW:

Concentration: 0.8 mg/mL

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification method: Affinity purification

Application: WB, IHC, ELISA

Dilution: WB 1:1000-1:5000, IHC 1:50-1:200

Storage: Store at -20°C. Avoid freeze / thaw cycles.

FLNA Polyclonal Antibody DataSheet