FLNA Polyclonal Antibody | G-AB-07255

FLNA Polyclonal Antibody | G-AB-07255 | Gentaur Antibodies

Overview: The protein encoded by this gene is an actin-binding protein that crosslinks actin filaments and links actin filaments to membrane glycoproteins. The encoded protein is involved in remodeling the cytoskeleton to effect changes in cell shape and migration. This protein interacts with integrins, transmembrane receptor complexes, and second messengers. Defects in this gene are a cause of several syndromes, including periventricular nodular heterotopias (PVNH1, PVNH4) , otopalatodigital syndromes (OPD1, OPD2) , frontometaphyseal dysplasia (FMD) , Melnick-Needles syndrome (MNS) , and X-linked congenital idiopathic intestinal pseudoobstruction (CIIPX) . Two transcript variants encoding different isoforms have been found for this gene.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Signal Transduction

Synonyms: FLNA, ABP-280, ABPX, CSBS, CVD1, FLN, FLN-A, FLN1, FMD, MNS, NHBP, OPD, OPD1, OPD2, XLVD, XMVD, filamin-A

Reactivity: Human, Mouse

Host: Rabbit

Isotype: IgG

Gene ID: 2316

Accession #:

Clonality:

Immunogen: Recombinant fusion protein of human FLNA (NP_001104026.1) .

Clone #:

Conjugation: Unconjugated

Swissprot: P21333

Santa Cruz:

Calculated MW: 280 kDa

Observed MW: 315 kDa

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: WB, IF

Dilution: WB 1:500-1:2000 IF 1:50-1:200

Storage: Store at -20°C. Avoid freeze / thaw cycles.

FLNA Polyclonal Antibody DataSheet