FMO1 Polyclonal Antibody | G-AB-11365

FMO1 Polyclonal Antibody | G-AB-11365 | Gentaur Antibodies

Overview: Metabolic N-oxidation of the diet-derived amino-trimethylamine (TMA) is mediated by flavin-containing monooxygenase and is subject to an inherited FMO3 polymorphism in man resulting in a small subpopulation with reduced TMA N-oxidation capacity resulting in fish odor syndrome Trimethylaminuria. Three forms of the enzyme, FMO1 found in fetal liver, FMO2 found in adult liver, and FMO3 are encoded by genes clustered in the 1q23-q25 region. Flavin-containing monooxygenases are NADPH-dependent flavoenzymes that catalyzes the oxidation of soft nucleophilic heteroatom centers in drugs, pesticides, and xenobiotics. Several transcript variants encoding different isoforms have been found for this gene.

Category Type: Polyclonal Antibody

Research Areas:

Synonyms: FMO1

Reactivity: Human, Mouse

Host: Rabbit

Isotype: IgG

Gene ID: 2326

Accession #:

Clonality:

Immunogen: Recombinant fusion protein of human FMO1 (NP_002012.1) .

Clone #:

Conjugation: Unconjugated

Swissprot: Q01740

Santa Cruz:

Calculated MW: 52 kDa/60 kDa

Observed MW: 60 kDa

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: WB, IF

Dilution: WB 1:500-1:2000 IF 1:50-1:100

Storage: Store at -20°C. Avoid freeze / thaw cycles.

FMO1 Polyclonal Antibody DataSheet