FMO5 Polyclonal Antibody | G-AB-11800

FMO5 Polyclonal Antibody | G-AB-11800 | Gentaur Antibodies

Overview: Metabolic N-oxidation of the diet-derived amino-trimethylamine (TMA) is mediated by flavin-containing monooxygenase and is subject to an inherited FMO3 polymorphism in man resulting in a small subpopulation with reduced TMA N-oxidation capacity resulting in fish odor syndrome Trimethylaminuria. Three forms of the enzyme, FMO1 found in fetal liver, FMO2 found in adult liver, and FMO3 are encoded by genes clustered in the 1q23-q25 region. Flavin-containing monooxygenases are NADPH-dependent flavoenzymes that catalyzes the oxidation of soft nucleophilic heteroatom centers in drugs, pesticides, and xenobiotics. Alternative splicing results in multiple transcript variants.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Metabolism, Signal Transduction

Synonyms: FMO5

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID: 2330

Accession #:

Clonality:

Immunogen: Recombinant fusion protein of human FMO5 (NP_001138302.1) .

Clone #:

Conjugation: Unconjugated

Swissprot: P49326

Santa Cruz:

Calculated MW:

Observed MW:

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: IF

Dilution: IF 1:50-1:200

Storage: Store at -20°C. Avoid freeze / thaw cycles.

FMO5 Polyclonal Antibody DataSheet