FMR1 Polyclonal Antibody | G-AB-10936

FMR1 Polyclonal Antibody | G-AB-10936 | Gentaur Antibodies

Overview: The protein encoded by this gene binds RNA and is associated with polysomes. The encoded protein may be involved in mRNA trafficking from the nucleus to the cytoplasm. A trinucleotide repeat (CGG) in the 5' UTR is normally found at 6-53 copies, but an expansion to 55-230 repeats is the cause of fragile X syndrome. Expansion of the trinucleotide repeat may also cause one form of premature ovarian failure (POF1) . Multiple alternatively spliced transcript variants that encode different protein isoforms and which are located in different cellular locations have been described for this gene.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Epigenetics and Nuclear Signaling, Neuroscience

Synonyms: FMRP, FRAXA, POF, POF1, FMR1, POFX

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID: 2332

Accession #:

Clonality:

Immunogen: A synthetic peptide of human FMR1 (NP_002015.1) .

Clone #:

Conjugation: Unconjugated

Swissprot: Q06787

Santa Cruz:

Calculated MW: 58 kDa/61 kDa/66 kDa/68 kDa/69 kDa/70 kDa/71 kDa

Observed MW: 71 kDa

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: WB, IHC

Dilution: WB 1:500-1:1000 IHC 1:50-1:200

Storage: Store at -20°C. Avoid freeze / thaw cycles.

FMR1 Polyclonal Antibody DataSheet