FOXK1 Polyclonal Antibody | G-AB-04686

FOXK1 Polyclonal Antibody | G-AB-04686 | Gentaur Antibodies

Overview: The FOX family of transcription factors share a common DIUA binding domain termed a winged-helix or forkhead domain. Many FOX proteins play important roles in development, metabolism, cancer and aging. In skeletal muscles, undifferentiated myogenic stem cells (satellite cells) can mobilize to regenerate myofibers in response to injury. FOXK1 is expressed in these cells and regulates cell cycle progression through an interaction with its downstream target the cyclin-dependent kinase inhibitor p21 (CIP) . Loss of FOXK1 in mice results in growth retardation and a severe impairment in skeletal muscle regeneration following injury. FOXK1 also shows expression in immature tissues of brain, eye, heart, lung and thymus. It also is predominantly expressed in many malignant tissues, such as tumors of the brain, colon and lymph node.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Epigenetics and Nuclear Signaling

Synonyms: A630048H08Rik, AI463295, ENSMUSG00000075577, FHX, Fork head, Forkhead box protein K1, FOXJ2 forkhead factor, FOXK1, FOXK1, Gm10868, MNF, Myocyte nuclear factor

Reactivity: Human, Mouse

Host: Rabbit

Isotype: IgG

Gene ID:

Accession #: NP001032242

Clonality: Polyclonal

Immunogen: Synthetic peptide of human FOXK1

Clone #:

Conjugation: Unconjugated

Swissprot: P85037

Santa Cruz:

Calculated MW: 75 kDa

Observed MW: Refer to figures

Concentration: 1.5 mg/mL

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Purification method: Antigen affinity purification

Application: WB, ELISA

Dilution: WB 1:500-1:2000, ELISA 1:5000-1:10000

Storage: Store at -20°C. Avoid freeze / thaw cycles.

FOXK1 Polyclonal Antibody DataSheet