FREM1 Polyclonal Antibody | G-AB-09492

FREM1 Polyclonal Antibody | G-AB-09492 | Gentaur Antibodies

Overview: This gene encodes a basement membrane protein that may play a role in craniofacial and renal development. Mutations in this gene have been associated with bifid nose with or without anorectal and renal anomalies. Alternatively spliced transcript variants encoding different isoforms have been described. PubMed ID 19940113 describes one such variant that initiates transcription within a distinct, internal exon; the resulting shorter isoform (named Toll-like/interleukin-1 receptor regulator, TILRR) is suggested to be a co-receptor of the interleukin 1 receptor family and may regulate receptor function and Toll-like receptor/interleukin 1 receptor Signal Transduction, contributing to the control of inflammatory response activation.

Category Type: Polyclonal Antibody

Research Areas:

Synonyms: FREM1, BNAR, C9orf143, C9orf145, C9orf154, MOTA, TILRR, TRIGNO2

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID: 158326

Accession #:

Clonality:

Immunogen: Recombinant fusion protein of human FREM1 (NP_659403.4) .

Clone #:

Conjugation: Unconjugated

Swissprot: Q5H8C1

Santa Cruz:

Calculated MW: 25 kDa/42 kDa/80 kDa/244 kDa

Observed MW: 72 kDa

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: WB

Dilution: WB 1:500-1:2000

Storage: Store at -20°C. Avoid freeze / thaw cycles.

FREM1 Polyclonal Antibody DataSheet