FZD6 Polyclonal Antibody | G-AB-01526

FZD6 Polyclonal Antibody | G-AB-01526 | Gentaur Antibodies

Overview: This gene represents a member of the 'frizzled' gene family, which encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The protein encoded by this family member contains a signal peptide, a cysteine-rich domain in the N-terminal extracellular region, and seven transmembrane domains, but unlike other family members, this protein does not contain a C-terminal PDZ domain-binding motif. This protein functions as a negative regulator of the canonical Wnt/beta-catenin signaling cascade, thereby inhibiting the processes that trigger oncogenic transformation, cell proliferation, and inhibition of apoptosis. Alternative splicing results in multiple transcript variants, some of which do not encode a protein with a predicted signal peptide.

Category Type: Polyclonal Antibody

Research Areas: Stem Cells

Synonyms: Frizzled 6 seven transmembrane spanning receptor, Frizzled drosophila homolog of 6, Frizzled family receptor 6, Frizzled homolog 6 (Drosophila) , Frizzled homolog 6, Frizzled-6, Frizzled6, Fz 6, Fz-6, Fz6, FZD 6, Fzd6, FZD6, Hfz 6, hFz6, NDNC10

Reactivity: Human, Mouse

Host: Rabbit

Isotype: IgG

Gene ID:

Accession #: NP_001158087

Clonality: Polyclonal

Immunogen: Synthetic peptide of human FZD6

Clone #:

Conjugation: Unconjugated

Swissprot: O60353

Santa Cruz: sc-32152/sc-32148/sc-32150

Calculated MW:

Observed MW:

Concentration: 0.2 mg/mL

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification method: Affinity purification

Application: IHC, ELISA

Dilution: IHC 1:100-1:300

Storage: Store at -20°C. Avoid freeze / thaw cycles.

FZD6 Polyclonal Antibody DataSheet