GITR/TNFRSF18 Polyclonal Antibody | G-AB-09117

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€183.12 - €390.60
SKU:
G-AB-09117
Availability:
3 to 5 Working Days
Host:
Rabbit
Reactivity:
Mouse
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GITR/TNFRSF18 Polyclonal Antibody | G-AB-09117 | Gentaur Antibodies

Overview: This gene encodes a member of the TNF-receptor superfamily. The encoded receptor has been shown to have increased expression upon T-cell activation, and it is thought to play a key role in dominant immunological self-tolerance maintained by CD25 (+) CD4 (+) regulatory T cells. Knockout studies in mice also suggest the role of this receptor is in the regulation of CD3-driven T-cell activation and programmed cell death. Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.

Category Type: Polyclonal Antibody

Research Areas:

Synonyms: TNFRSF18, AITR, CD357, GITR, GITR-D

Reactivity: Mouse

Host: Rabbit

Isotype: IgG

Gene ID: 8784

Accession #:

Clonality:

Immunogen: Recombinant fusion protein of human GITR/TNFRSF18 (NP_683699.1) .

Clone #:

Conjugation: Unconjugated

Swissprot: Q9Y5U5

Santa Cruz:

Calculated MW: 25 kDa/26 kDa

Observed MW: 30 kDa

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: WB

Dilution: WB 1:500-1:2000

Storage: Store at -20°C. Avoid freeze / thaw cycles.

GITR/TNFRSF18 Polyclonal Antibody DataSheet