GJB6 Polyclonal Antibody | G-AB-01263

GJB6 Polyclonal Antibody | G-AB-01263 | Gentaur Antibodies

Overview: Gap junctions allow the transport of ions and metabolites between the cytoplasm of adjacent cells. They are formed by two hemichannels, made up of six connexin proteins assembled in groups. Each connexin protein has four transmembrane segments, two extracellular loops, a cytoplasmic loop formed between the two inner transmembrane segments, and the N- and C-terminus both being in the cytoplasm. The specificity of the gap junction is determined by which connexin proteins comprise the hemichannel. In the past, connexin protein names were based on their molecular weight, however the new nomenclature uses sequential numbers based on which form (alpha or beta) of the gap junction is present. This gene encodes one of the connexin proteins. Mutations in this gene have been found in some forms of deafness and in some families with hidrotic ectodermal dysplasia.

Category Type: Polyclonal Antibody

Research Areas: Neuroscience, Signal Transduction

Synonyms: Connexin 30, Connexin-30, Cx30, CXB6, DFNA3, DFNA3B, DFNB1B, ECTD2, ectodermal dysplasia 2, hidrotic (Clouston syndrome) , ED2, EDH, Gap junction beta 6 protein, Gap junction beta-6 protein, gap junction protein, beta 6 (connexin 30) , gap junction protein, beta 6, Gap junction protein, beta 6, 30kDa, GJB6, HED, HED2, NSRD1

Reactivity: Human, Mouse

Host: Rabbit

Isotype: IgG

Gene ID:

Accession #: NP_006774

Clonality: Polyclonal

Immunogen: Synthetic peptide of human GJB6

Clone #:

Conjugation: Unconjugated

Swissprot: O95452

Santa Cruz: sc-84801/sc-84802

Calculated MW: 30 kDa

Observed MW:

Concentration: 0.3 mg/mL

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification method: Affinity purification

Application: WB, IHC, ELISA

Dilution: WB 1:500-1:2000, IHC 1:25-1:100

Storage: Store at -20°C. Avoid freeze / thaw cycles.

GJB6 Polyclonal Antibody DataSheet