GLDC Polyclonal Antibody | G-AB-12440
- 3 to 5 Working Days
- Human, Mouse, Rat
GLDC Polyclonal Antibody | G-AB-12440 | Gentaur Antibodies
Overview: Degradation of glycine is brought about by the glycine cleavage system, which is composed of four mitochondrial protein components: P protein (a pyridoxal phosphate-dependent glycine decarboxylase) , H protein (a lipoic acid-containing protein) , T protein (a tetrahydrofolate-requiring enzyme) , and L protein (a lipoamide dehydrogenase) . The protein encoded by this gene is the P protein, which binds to glycine and enables the methylamine group from glycine to be transferred to the T protein. Defects in this gene are a cause of nonketotic hyperglycinemia (NKH) .
Category Type: Polyclonal Antibody
Research Areas: Cancer, Metabolism, Signal Transduction
Synonyms: GLDC, GCE, GCSP, HYGN1
Reactivity: Human, Mouse, Rat
Gene ID: 2731
Immunogen: Recombinant fusion protein of human GLDC (NP_000161.2) .
Calculated MW: 112 kDa
Observed MW: 113 kDa
Concentration: 1 mg/mL
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Purification method: Affinity purification
Dilution: WB 1:500-1:2000
Storage: Store at -20°C. Avoid freeze / thaw cycles.