GLI2 Polyclonal Antibody | G-AB-11142

GLI2 Polyclonal Antibody | G-AB-11142 | Gentaur Antibodies

Overview: This gene encodes a protein which belongs to the C2H2-type zinc finger protein subclass of the Gli family. Members of this subclass are characterized as transcription factors which bind DNA through zinc finger motifs. These motifs contain conserved H-C links. Gli family zinc finger proteins are mediators of Sonic hedgehog (Shh) signaling and they are implicated as potent oncogenes in the embryonal carcinoma cell. The protein encoded by this gene localizes to the cytoplasm and activates patched Drosophila homolog (PTCH) gene expression. It is also thought to play a role during embryogenesis. The encoded protein is associated with several phenotypes- Greig cephalopolysyndactyly syndrome, Pallister-Hall syndrome, preaxial polydactyly type IV, postaxial polydactyly types A1 and B.

Category Type: Polyclonal Antibody

Research Areas:

Synonyms: GLI2, CJS, HPE9, PHS2, THP1, THP2, Gli2

Reactivity: Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID: 14633

Accession #:

Clonality:

Immunogen: Recombinant protein of mouse GLI2

Clone #:

Conjugation: Unconjugated

Swissprot: Q0VGT2

Santa Cruz:

Calculated MW: 168 kDa

Observed MW: 90 kDa

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: WB

Dilution: WB 1:500-1:2000

Storage: Store at -20°C. Avoid freeze / thaw cycles.

GLI2 Polyclonal Antibody DataSheet