GPC3 Polyclonal Antibody | G-AB-07027

GPC3 Polyclonal Antibody | G-AB-07027 | Gentaur Antibodies

Overview: Cell surface heparan sulfate proteoglycans are composed of a membrane-associated protein core substituted with a variable number of heparan sulfate chains. Members of the glypican-related integral membrane proteoglycan family (GRIPS) contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol linkage. These proteins may play a role in the control of cell division and growth regulation. The protein encoded by this gene can bind to and inhibit the dipeptidyl peptidase activity of CD26, and it can induce apoptosis in certain cell types. Deletion mutations in this gene are associated with Simpson-Golabi-Behmel syndrome, also known as Simpson dysmorphia syndrome. Alternative splicing results in multiple transcript variants.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Developmental Biology, Signal Transduction, Stem Cells

Synonyms: DGSX, Glypican proteoglycan 3, Glypican-3 [Precursor], Gpc3, GPC3, GTR2 2, GTR2-2, Heparan sulphate proteoglycan, Intestinal protein OCI 5, Intestinal protein OCI-5, MXR7, OCI 5, OCI-5, OCI5, SDYS, Secreted glypican-3, SGB, SGBS, SGBS1

Reactivity: Human, Mouse

Host: Rabbit

Isotype: IgG

Gene ID:

Accession #: NP004475

Clonality: Polyclonal

Immunogen: Synthetic peptide of human GPC3

Clone #:

Conjugation: Unconjugated

Swissprot: P51654

Santa Cruz:

Calculated MW:

Observed MW:

Concentration: 1.8 mg/mL

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Purification method: Antigen affinity purification

Application: IHC, ELISA

Dilution: IHC 1:40-1:200, ELISA 1:5000-1:10000

Storage: Store at -20°C. Avoid freeze / thaw cycles.

GPC3 Polyclonal Antibody DataSheet