GRAP Polyclonal Antibody | G-AB-09048

GRAP Polyclonal Antibody | G-AB-09048 | Gentaur Antibodies

Overview: This gene encodes a member of the GRB2/Sem5/Drk family and functions as a cytoplasmic signaling protein which contains an SH2 domain flanked by two SH3 domains. The SH2 domain interacts with ligand-activated receptors for stem cell factor and erythropoietin, and facilitates the formation of a stable complex with the BCR-ABL oncoprotein. This protein also associates with the Ras guanine nucleotide exchange factor SOS1 (son of sevenless homolog 1) through its N-terminal SH3 domain. In general, it couples signals from receptor and cytoplasmic tyrosine kinases to the Ras signaling pathway.

Category Type: Polyclonal Antibody

Research Areas: Signal Transduction

Synonyms: GRAP

Reactivity: Human

Host: Rabbit

Isotype: IgG

Gene ID: 10750

Accession #:

Clonality:

Immunogen: Recombinant fusion protein of human GRAP (NP_006604.1) .

Clone #:

Conjugation: Unconjugated

Swissprot: Q13588

Santa Cruz:

Calculated MW: 25 kDa

Observed MW: 36 kDa

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: WB

Dilution: WB 1:200-1:2000

Storage: Store at -20°C. Avoid freeze / thaw cycles.

GRAP Polyclonal Antibody DataSheet