GRIA4 Polyclonal Antibody | G-AB-08856

GRIA4 Polyclonal Antibody | G-AB-08856 | Gentaur Antibodies

Overview: Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes composed of multiple subunits, arranged to form ligand-gated ion channels. The classification of glutamate receptors is based on their activation by different pharmacologic agonists. The subunit encoded by this gene belongs to a family of AMPA (alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate) -sensitive glutamate receptors, and is subject to RNA editing (AGA->GGA; R->G) . Alternative splicing of this gene results in transcript variants encoding different isoforms, which may vary in their Signal Transduction properties. Some haplotypes of this gene show a positive association with schizophrenia.

Category Type: Polyclonal Antibody

Research Areas: Neuroscience, Signal Transduction

Synonyms: GRIA4, GLUR4, GLUR4C, GLURD, GluA4

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID: 2893

Accession #:

Clonality:

Immunogen: Recombinant fusion protein of human GRIA4 (NP_001070712.1) .

Clone #:

Conjugation: Unconjugated

Swissprot: P48058

Santa Cruz:

Calculated MW: 49 kDa/100 kDa

Observed MW: 101 kDa

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: WB

Dilution: WB 1:1000-1:4000

Storage: Store at -20°C. Avoid freeze / thaw cycles.

GRIA4 Polyclonal Antibody DataSheet