GRK1 Polyclonal Antibody | G-AB-02777

GRK1 Polyclonal Antibody | G-AB-02777 | Gentaur Antibodies

Overview: This gene encodes a member of the guanine nucleotide-binding protein (G protein) -coupled receptor kinase subfamily of the Ser/Thr protein kinase family. The protein phosphorylates rhodopsin and initiates its deactivation. Defects in GRK1 are known to cause Oguchi disease 2 (also known as stationary night blindness Oguchi type-2) . Retina-specific kinase involved in the signal turnoff via phosphorylation of rhodopsin (RHO) , the G protein- coupled receptor that initiates the phototransduction cascade. This rapid desensitization is essential for scotopic vision and permits rapid adaptation to changes in illumination.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Neuroscience, Signal Transduction

Synonyms: RK, RHOK, GPRK1

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID:

Accession #: NP_002920

Clonality: Polyclonal

Immunogen: Synthetic peptide of human GRK1

Clone #:

Conjugation: Unconjugated

Swissprot: Q15835

Santa Cruz: sc-84290/sc-84291/sc-13078/sc-561

Calculated MW:

Observed MW:

Concentration: 0.6 mg/mL

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification method: Affinity purification

Application: IHC, ELISA

Dilution: IHC 1:50-1:200

Storage: Store at -20°C. Avoid freeze / thaw cycles.

GRK1 Polyclonal Antibody DataSheet