GRPR Polyclonal Antibody | G-AB-01290

GRPR Polyclonal Antibody | G-AB-01290 | Gentaur Antibodies

Overview: Gastrin-releasing peptide (GRP) regulates numerous functions of the gastrointestinal and central nervous systems, including release of gastrointestinal hormones, smooth muscle cell contraction, and epithelial cell proliferation and is a potent mitogen for neoplastic tissues. The effects of GRP are mediated through the gastrin-releasing peptide receptor. This receptor is a glycosylated, 7-transmembrane G-protein coupled receptor that activates the phospholipase C signaling pathway. The receptor is aberrantly expressed in numerous cancers such as those of the lung, colon, and prostate. An individual with autism and multiple exostoses was found to have a balanced translocation between chromosome 8 and a chromosome X breakpoint located within the gastrin-releasing peptide receptor gene.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Neuroscience, Signal Transduction

Synonyms: BB2, Bombesin BB2 receptor, bombesin receptor 2, Gastrin Releasing Peptide Receptor, Gastrin-releasing peptide receptor, GRP preferring bombesin receptor, GRP R, GRP-preferring bombesin receptor, GRP-R, Grp/bombesin receptor, Grpr, GRPR

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID:

Accession #: NP_005305

Clonality: Polyclonal

Immunogen: Synthetic peptide of human GRPR

Clone #:

Conjugation: Unconjugated

Swissprot: P30550

Santa Cruz: sc-26835/sc-26836/sc-32903

Calculated MW: 43 kDa

Observed MW:

Concentration: 1.1 mg/mL

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification method: Affinity purification

Application: WB, IHC, ELISA

Dilution: WB 1:200-1:1000, IHC 1:50-1:200

Storage: Store at -20°C. Avoid freeze / thaw cycles.

GRPR Polyclonal Antibody DataSheet