GSK3 alpha Polyclonal Antibody | G-AB-02779

GSK3 alpha Polyclonal Antibody | G-AB-02779 | Gentaur Antibodies

Overview: This gene encodes a multifunctional Ser/Thr protein kinase that is implicated in the control of several regulatory proteins including glycogen synthase, and transcription factors, such as JUN. It also plays a role in the WNT and PI3K signaling pathways, as well as regulates the production of beta-amyloid peptides associated with Alzheimer's disease. May also mediate the development of insulin resistance by regulating activation of transcription factors. In Wnt signaling, regulates the level and transcriptional activity of nuclear CTNNB1/beta-catenin. Facilitates amyloid precursor protein (APP) processing and the generation of APP-derived amyloid plaques found in Alzheimer disease. May be involved in the regulation of replication in pancreatic beta-cells. Is necessary for the establishment of neuronal polarity and axon outgrowth.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Cell Biology, Cardiovascular, Signal Transduction, Stem Cells

Synonyms: DKFZp686D0638, Glycogen synthase kinase 3 alpha, Glycogen synthase kinase-3 alpha, GSK 3 alpha, GSK 3A, GSK-3 alpha, Gsk3a, GSK3A, GSK3alpha, Serine/threonine protein kinase GSK3A

Reactivity: Human

Host: Rabbit

Isotype: IgG

Gene ID:

Accession #: NP_063937

Clonality: Polyclonal

Immunogen: Synthetic peptide of human GSK3A

Clone #:

Conjugation: Unconjugated

Swissprot: P49840

Santa Cruz: sc-1846/sc-1844/sc-7879

Calculated MW:

Observed MW:

Concentration: 0.4 mg/mL

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification method: Affinity purification

Application: IHC, ELISA

Dilution: IHC 1:50-1:200

Storage: Store at -20°C. Avoid freeze / thaw cycles.

GSK3 alpha Polyclonal Antibody DataSheet