GSTM3 Polyclonal Antibody | G-AB-10404

GSTM3 Polyclonal Antibody | G-AB-10404 | Gentaur Antibodies

Overview: Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-transferase that belongs to the mu class. The mu class of enzymes functions in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding the mu class of enzymes are organized in a gene cluster on chromosome 1p13.3 and are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of certain drugs. Mutations of this class mu gene have been linked with a slight increase in a number of cancers, likely due to exposure with environmental toxins. Alternative splicing results in multiple transcript variants.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Metabolism, Signal Transduction

Synonyms: GSTM3, GST5, GSTB, GSTM3-3, GTM3

Reactivity: Human, Mouse

Host: Rabbit

Isotype: IgG

Gene ID: 2947

Accession #:

Clonality:

Immunogen: Recombinant fusion protein of human GSTM3 (NP_000840.2) .

Clone #:

Conjugation: Unconjugated

Swissprot: P21266

Santa Cruz:

Calculated MW: 26 kDa

Observed MW: 25 kDa

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: WB

Dilution: WB 1:500-1:2000

Storage: Store at -20°C. Avoid freeze / thaw cycles.

GSTM3 Polyclonal Antibody DataSheet