GTF2A2 Polyclonal Antibody | G-AB-11805

GTF2A2 Polyclonal Antibody | G-AB-11805 | Gentaur Antibodies

Overview: Accurate transcription initiation on TATA-containing class II genes involves the ordered assembly of RNA polymerase II (POLR2A; MIM 180660) and the general initiation factors TFIIA, TFIIB (MIM 189963) , TFIID (MIM 313650) , TFIIE (MIM 189962) , TFIIF (MIM 189968) , TFIIG/TFIIJ, and TFIIH (MIM 189972) . The first step involves recognition of the TATA element by the TATA-binding subunit (TBP; MIM 600075) and may be regulated by TFIIA, a factor that interacts with both TBP and a TBP-associated factor (TAF; MIM 600475) in TFIID. TFIIA has 2 subunits (43 and 12 kD) in yeast and 3 subunits in higher eukaryotes. In HeLa extracts, it consists of a 35-kD alpha subunit and a 19-kD beta subunit encoded by the N- and C-terminal regions of GTF2A1 (MIM 600520) , respectively, and a 12-kD gamma subunit encoded by GTF2A2 (DeJong et al., 1995 [PubMed 7724559]) .

Category Type: Polyclonal Antibody

Research Areas: Epigenetics and Nuclear Signaling

Synonyms: GTF2A2, HsT18745, T18745, TF2A2, TFIIA, TFIIA-12, TFIIA-gamma, TFIIAS

Reactivity: Human

Host: Rabbit

Isotype: IgG

Gene ID: 2958

Accession #:

Clonality:

Immunogen: Recombinant fusion protein of human GTF2A2 (NP_004483.1) .

Clone #:

Conjugation: Unconjugated

Swissprot: P52657

Santa Cruz:

Calculated MW: 12 kDa

Observed MW: 12 kDa

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: WB

Dilution: WB 1:500-1:2000

Storage: Store at -20°C. Avoid freeze / thaw cycles.

GTF2A2 Polyclonal Antibody DataSheet