H3K4 Me3 Antibody | 806-A2357
TriMethyl-Histone H3-K4 Rabbit pAb
Liquid, in PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
A synthetic methylated peptide corresponding to residues surrounding K4 of human histone H3
Human, Mouse, Rat, Other (Wide Range)
Store at -20℃. Avoid freeze / thaw cycles.
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
ChIP, IF, IHC, IP, WB
HeLa acid extract, NIH/3T3 acid extract, C6 acid extract, H3 protein
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H3 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is located separately from the other H3 genes that are in the histone gene cluster on chromosome 6p22-p21.3.