HAMP Polyclonal Antibody | G-AB-09272

HAMP Polyclonal Antibody | G-AB-09272 | Gentaur Antibodies

Overview: The product encoded by this gene is involved in the maintenance of iron homeostasis, and it is necessary for the regulation of iron storage in macrophages, and for intestinal iron absorption. The preproprotein is post-translationally cleaved into mature peptides of 20, 22 and 25 amino acids, and these active peptides are rich in cysteines, which form intramolecular bonds that stabilize their beta-sheet structures. These peptides exhibit antimicrobial activity against bacteria and fungi. Mutations in this gene cause hemochromatosis type 2B, also known as juvenile hemochromatosis, a disease caused by severe iron overload that results in cardiomyopathy, cirrhosis, and endocrine failure.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Cardiovascular, Metabolism, Signal Transduction

Synonyms: HAMP, HEPC, HFE2B, LEAP1, PLTR, hepcidin

Reactivity: Human, Mouse

Host: Rabbit

Isotype: IgG

Gene ID: 57817

Accession #:

Clonality:

Immunogen: Recombinant fusion protein of human HAMP (NP_066998.1) .

Clone #:

Conjugation: Unconjugated

Swissprot: P81172

Santa Cruz:

Calculated MW: 9 kDa

Observed MW: 10 kDa

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: WB

Dilution: WB 1:500-1:2000

Storage: Store at -20°C. Avoid freeze / thaw cycles.

HAMP Polyclonal Antibody DataSheet