HAX1 Polyclonal Antibody | G-AB-10709

HAX1 Polyclonal Antibody | G-AB-10709 | Gentaur Antibodies

Overview: The protein encoded by this gene is known to associate with hematopoietic cell-specific Lyn substrate 1, a substrate of Src family tyrosine kinases. It also interacts with the product of the polycystic kidney disease 2 gene, mutations in which are associated with autosomal-dominant polycystic kidney disease, and with the F-actin-binding protein, cortactin. It was earlier thought that this gene product is mainly localized in the mitochondria, however, recent studies indicate it to be localized in the cell body. Mutations in this gene result in autosomal recessive severe congenital neutropenia, also known as Kostmann disease. Two transcript variants encoding different isoforms have been found for this gene.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Cell Biology, Epigenetics and Nuclear Signaling, Metabolism

Synonyms: HAX1, HCLSBP1, HS1BP1, SCN3

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID: 10456

Accession #:

Clonality:

Immunogen: Recombinant fusion protein of human HAX1 (NP_006109.2) .

Clone #:

Conjugation: Unconjugated

Swissprot: O00165

Santa Cruz:

Calculated MW: 14 kDa/21 kDa/26 kDa/28 kDa/31 kDa/32 kDa

Observed MW: 36 kDa

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: WB, IHC, IF

Dilution: WB 1:500-1:2000 IHC 1:50-1:200 IF 1:10-1:100

Storage: Store at -20°C. Avoid freeze / thaw cycles.

HAX1 Polyclonal Antibody DataSheet