HBA2 Polyclonal Antibody | G-AB-12195
- 3 to 5 Working Days
- Mouse, Rat
HBA2 Polyclonal Antibody | G-AB-12195 | Gentaur Antibodies
Overview: The human alpha globin gene cluster located on chromosome 16 spans about 30 kb and includes seven loci: 5'- zeta - pseudozeta - mu - pseudoalpha-1 - alpha-2 - alpha-1 - theta - 3'. The alpha-2 (HBA2) and alpha-1 (HBA1) coding sequences are identical. These genes differ slightly over the 5' untranslated regions and the introns, but they differ significantly over the 3' untranslated regions. Two alpha chains plus two beta chains constitute HbA, which in normal adult life comprises about 97% of the total hemoglobin; alpha chains combine with delta chains to constitute HbA-2, which with HbF (fetal hemoglobin) makes up the remaining 3% of adult hemoglobin. Alpha thalassemias result from deletions of each of the alpha genes as well as deletions of both HBA2 and HBA1; some nondeletion alpha thalassemias have also been reported.
Category Type: Polyclonal Antibody
Research Areas: Cancer, Cardiovascular
Synonyms: HBA2, HBA-T2, HBH
Reactivity: Mouse, Rat
Gene ID: 3040
Immunogen: Recombinant fusion protein of human HBA2 (NP_000508.1) .
Concentration: 1 mg/mL
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Purification method: Affinity purification
Dilution: IHC 1:50-1:100
Storage: Store at -20°C. Avoid freeze / thaw cycles.