HDAC3 Polyclonal Antibody | G-AB-07843
Gentaur Antibodies
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Gentaur Antibodies
HDAC3 Polyclonal Antibody | G-AB-07843
- SKU:
- G-AB-07843
- Availability:
- 3 to 5 Working Days
- Host:
- Rabbit
- Reactivity:
- Human, Mouse, Rat
HDAC3 Polyclonal Antibody | G-AB-07843 | Gentaur Antibodies
Overview: Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family. It has histone deacetylase activity and represses transcription when tethered to a promoter. It may participate in the regulation of transcription through its binding with the zinc-finger transcription factor YY1. This protein can also down-regulate p53 function and thus modulate cell growth and apoptosis. This gene is regarded as a potential tumor suppressor gene.
Category Type: Polyclonal Antibody
Research Areas: Cancer, Cardiovascular, Epigenetics and Nuclear Signaling, Metabolism, Stem Cells
Synonyms: HD3, RPD3, RPD3-2, HDAC3
Reactivity: Human, Mouse, Rat
Host: Rabbit
Isotype: IgG
Gene ID: 8841
Accession #:
Clonality:
Immunogen: A synthetic peptide of human HDAC3 (NP_003874.2) .
Clone #:
Conjugation: Unconjugated
Swissprot: O15379
Santa Cruz:
Calculated MW: 48 kDa/49 kDa
Observed MW: 48 kDa
Concentration: 1 mg/mL
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Purification method: Affinity purification
Application: WB, IHC, IF
Dilution: WB 1:500-1:2000 IHC 1:50-1:200 IF 1:50-1:200
Storage: Store at -20°C. Avoid freeze / thaw cycles.
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