HDAC4 Polyclonal Antibody | G-AB-11965

HDAC4 Polyclonal Antibody | G-AB-11965 | Gentaur Antibodies

Overview: Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. This protein does not bind DNA directly, but through transcription factors MEF2C and MEF2D. It seems to interact in a multiprotein complex with RbAp48 and HDAC3.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Cardiovascular, Epigenetics and Nuclear Signaling, Stem Cells

Synonyms: HDAC4, AHO3, BDMR, HA6116, HD4, HDAC-4, HDAC-A, HDACA

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID: 9759

Accession #:

Clonality:

Immunogen: A synthetic peptide of human HDAC4 (NP_006028.2) .

Clone #:

Conjugation: Unconjugated

Swissprot: P56524

Santa Cruz:

Calculated MW:

Observed MW:

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: IHC, IF

Dilution: IHC 1:50-1:200 IF 1:50-1:200

Storage: Store at -20°C. Avoid freeze / thaw cycles.

HDAC4 Polyclonal Antibody DataSheet