HEXA Polyclonal Antibody | G-AB-07802

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$218.00 - $465.00
SKU:
G-AB-07802
Availability:
3 to 5 Working Days
Host:
Rabbit
Reactivity:
Human, Mouse, Rat
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HEXA Polyclonal Antibody | G-AB-07802 | Gentaur Antibodies

Overview: This gene encodes a member of the glycosyl hydrolase 20 family of proteins. The encoded preproprotein is proteolytically processed to generate the alpha subunit of the lysosomal enzyme beta-hexosaminidase. This enzyme, together with the cofactor GM2 activator protein, catalyzes the degradation of the ganglioside GM2, and other molecules containing terminal N-acetyl hexosamines. Mutations in this gene lead to an accumulation of GM2 ganglioside in neurons, the underlying cause of neurodegenerative disorders termed the GM2 gangliosidoses, including Tay-Sachs disease (GM2-gangliosidosis type I) . Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed.

Category Type: Polyclonal Antibody

Research Areas: Neuroscience

Synonyms: HEXA, TSD

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID: 3073

Accession #:

Clonality:

Immunogen: Recombinant fusion protein of human HEXA (NP_000511.2) .

Clone #:

Conjugation: Unconjugated

Swissprot: P06865

Santa Cruz:

Calculated MW:

Observed MW:

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: IHC

Dilution: IHC 1:50-1:200

Storage: Store at -20°C. Avoid freeze / thaw cycles.

HEXA Polyclonal Antibody DataSheet

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