Histone H2A.X Polyclonal Antibody | G-AB-05376

Histone H2A.X Polyclonal Antibody | G-AB-05376 | Gentaur Antibodies

Overview: Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene encodes a replication-independent histone that is a member of the histone H2A family, and generates two transcripts through the use of the conserved stem-loop termination motif, and the polyA addition motif.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Epigenetics and Nuclear Signaling

Synonyms: H2A histone family member X, H2A histone family member X, H2A.FX, H2A.X, H2a/x, H2AFX, H2AX, H2AX, Histone H2A.X

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID:

Accession #:

Clonality: Polyclonal

Immunogen: KLH conjugated Synthetic peptide corresponding to Mouse Histone H2A.X

Clone #:

Conjugation: Unconjugated

Swissprot: P16104, P27661

Santa Cruz:

Calculated MW: 15-18 kDa

Observed MW: 18 kDa

Concentration: 0.86 mg/mL

Buffer: PBS with 0.02% sodium azide, 1% BSA and 50% glycerol, pH7.4

Purification method: Affinity purification

Application: WB, IHC

Dilution: WB 1:500-1:2000, IHC 1:300-1:800

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Histone H2A.X Polyclonal Antibody DataSheet