Histone H4 Polyclonal Antibody | G-AB-11536
- 3 to 5 Working Days
- Human, Mouse, Rat
Histone H4 Polyclonal Antibody | G-AB-11536 | Gentaur Antibodies
Overview: Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4) . The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H4 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is found in a histone cluster on chromosome 1. This gene is one of four histone genes in the cluster that are duplicated; this record represents the telomeric copy.
Category Type: Polyclonal Antibody
Research Areas: Cancer, Epigenetics and Nuclear Signaling
Synonyms: HIST2H4B, H4/o, histone H4, Histone H4, HIST1H4A
Reactivity: Human, Mouse, Rat
Gene ID: 554313
Immunogen: Recombinant fusion protein of human HIST2H4B (NP_001029249.1) .
Concentration: 1 mg/mL
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Purification method: Affinity purification
Dilution: IF 1:50-1:100
Storage: Store at -20°C. Avoid freeze / thaw cycles.