Histone H2A.Z Polyclonal Antibody | G-AB-11208

Histone H2A.Z Polyclonal Antibody | G-AB-11208 | Gentaur Antibodies

Overview: Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4) . The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene encodes a replication-independent member of the histone H2A family that is distinct from other members of the family. Studies in mice have shown that this particular histone is required for embryonic development and indicate that lack of functional histone H2A leads to embryonic lethality.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Epigenetics and Nuclear Signaling

Synonyms: H2AFZ, H2A.Z-1, H2A.z, H2A/z, H2AZ, histone H2A.Z

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID: 3015

Accession #:

Clonality:

Immunogen: Recombinant fusion protein of human H2AFZ (NP_002097.1) .

Clone #:

Conjugation: Unconjugated

Swissprot: P0C0S5

Santa Cruz:

Calculated MW:

Observed MW:

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: IHC

Dilution: IHC 1:50-1:200

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Histone H2A.Z Polyclonal Antibody DataSheet