Histone H2AX Polyclonal Antibody | G-AB-07557

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$218.00 - $465.00
SKU:
G-AB-07557
Availability:
3 to 5 Working Days
Host:
Rabbit
Reactivity:
Human, Mouse, Rat
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Histone H2AX Polyclonal Antibody | G-AB-07557 | Gentaur Antibodies

Overview: Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene encodes a replication-independent histone that is a member of the histone H2A family, and generates two transcripts through the use of the conserved stem-loop termination motif, and the polyA addition motif.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Epigenetics and Nuclear Signaling

Synonyms: H2A.X, H2A/X, H2AX, Histone H2AX, H2AFX, histone H2AX, gamma H2A.X, γH2AX

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID: 3014

Accession #:

Clonality:

Immunogen: A synthetic peptide of human Histone H2AX (NP_002096.1) .

Clone #:

Conjugation: Unconjugated

Swissprot: P16104

Santa Cruz:

Calculated MW: 15 kDa

Observed MW: 15 kDa

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: WB, IF

Dilution: WB 1:500-1:1000 IF 1:50-1:200

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Histone H2AX Polyclonal Antibody DataSheet

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