HLA-DRA Polyclonal Antibody | G-AB-09194

HLA-DRA Polyclonal Antibody | G-AB-09194 | Gentaur Antibodies

Overview: HLA-DRA is one of the HLA class II alpha chain paralogues. This class II molecule is a heterodimer consisting of an alpha and a beta chain, both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages) . The alpha chain is approximately 33-35 kDa and its gene contains 5 exons. Exon 1 encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, and exon 4 encodes the transmembrane domain and the cytoplasmic tail. DRA does not have polymorphisms in the peptide binding part and acts as the sole alpha chain for DRB1, DRB3, DRB4 and DRB5.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Immunology

Synonyms: HLA-DRA, HLA-DRA1, major histocompatibility complex, class II, DR alpha

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID: 3122

Accession #:

Clonality:

Immunogen: Recombinant fusion protein of human HLA-DRA (NP_061984.2) .

Clone #:

Conjugation: Unconjugated

Swissprot: P01903

Santa Cruz:

Calculated MW: 28 kDa

Observed MW: 37 kDa

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: WB, IHC

Dilution: WB 1:500-1:2000 IHC 1:50-1:200

Storage: Store at -20°C. Avoid freeze / thaw cycles.

HLA-DRA Polyclonal Antibody DataSheet