HP Polyclonal Antibody | G-AB-02038

HP Polyclonal Antibody | G-AB-02038 | Gentaur Antibodies

Overview: This gene encodes a preproprotein, which is processed to yield both alpha and beta chains, which subsequently combine as a tetramer to produce haptoglobin. Haptoglobin functions to bind free plasma hemoglobin, which allows degradative enzymes to gain access to the hemoglobin, while at the same time preventing loss of iron through the kidneys and protecting the kidneys from damage by hemoglobin. Mutations in this gene and/or its regulatory regions cause ahaptoglobinemia or hypohaptoglobinemia. This gene has also been linked to diabetic nephropathy, the incidence of coronary artery disease in type 1 diabetes, Crohn's disease, inflammatory disease behavior, primary sclerosing cholangitis, susceptibility to idiopathic Parkinson's disease, and a reduced incidence of Plasmodium falciparum malaria. A similar duplicated gene is located next to this gene on chromosome 16. Multiple transcript variants encoding different isoforms have been found for this gene.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Cardiovascular

Synonyms: Binding peptide, BP, Haptoglobin alpha chain, Haptoglobin alpha (1S) beta, Haptoglobin alpha (2FS) beta, Haptoglobin beta chain, Haptoglobin, alpha polypeptide, Haptoglobin, beta polypeptide, HP, HP2 ALPHA2, HP2ALPHA2, HPA1S, HPT, HPT, MGC111141, Zonulin

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID:

Accession #: BC121125

Clonality: Polyclonal

Immunogen: Recombinant protein of human HP

Clone #:

Conjugation: Unconjugated

Swissprot: P00738

Santa Cruz: sc-68667/sc-134466/sc-134464

Calculated MW: 45 kDa

Observed MW:

Concentration: 0.4 mg/mL

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification method: Affinity purification

Application: WB, ELISA

Dilution: WB 1:200-1:1000

Storage: Store at -20°C. Avoid freeze / thaw cycles.

HP Polyclonal Antibody DataSheet

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