HSD11B1 Polyclonal Antibody | G-AB-06146

HSD11B1 Polyclonal Antibody | G-AB-06146 | Gentaur Antibodies

Overview: The protein encoded by this gene is a microsomal enzyme that catalyzes the conversion of the stress hormone cortisol to the inactive metabolite cortisone. In addition, the encoded protein can catalyze the reverse reaction, the conversion of cortisone to cortisol. Too much cortisol can lead to central obesity, and a particular variation in this gene has been associated with obesity and insulin resistance in children. Mutations in this gene and H6PD (hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)) are the cause of cortisone reductase deficiency. Alternate splicing results in multiple transcript variants encoding the same protein.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Metabolism, Signal Transduction

Synonyms: 11 beta HSD 1, 11 beta HSD1, 11 beta hydroxysteroid dehydrogenase 1, 11 DH, 11-beta hydroxysteroid dehydrogenase, type 1, 11-beta-HSD1, 11-beta-hydroxysteroid dehydrogenase 1, 11-DH, 11DH, Corticosteroid 11 beta dehydrogenase isozyme 1, Corticosteroid 11-beta-dehydrogenase isozyme 1, CORTRD2, DHI1, HDL, HSD 11, HSD11, HSD11B, HSD11B1, HSD11L, Hydroxysteroid (11 beta) dehydrogenase, Hydroxysteroid (11 beta) dehydrogenase 1, MGC13539, SDR26C1, short chain dehydrogenase/reductase family 26C, member 1

Reactivity: Human

Host: Rabbit

Isotype: IgG

Gene ID:

Accession #: BC012593

Clonality: Polyclonal

Immunogen: Fusion protein of human HSD11B1

Clone #:

Conjugation: Unconjugated

Swissprot: P28845

Santa Cruz:

Calculated MW:

Observed MW:

Concentration: 1.2 mg/mL

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Purification method: Antigen affinity purification

Application: IHC, ELISA

Dilution: IHC 1:50-1:200, ELISA 1:5000-1:10000

Storage: Store at -20°C. Avoid freeze / thaw cycles.

HSD11B1 Polyclonal Antibody DataSheet