HSD11B1 Polyclonal Antibody | G-AB-09345
Gentaur Antibodies
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Gentaur Antibodies
HSD11B1 Polyclonal Antibody | G-AB-09345
- SKU:
- G-AB-09345
- Availability:
- 3 to 5 Working Days
- Host:
- Rabbit
- Reactivity:
- Mouse
HSD11B1 Polyclonal Antibody | G-AB-09345 | Gentaur Antibodies
Overview: The protein encoded by this gene is a microsomal enzyme that catalyzes the conversion of the stress hormone cortisol to the inactive metabolite cortisone. In addition, the encoded protein can catalyze the reverse reaction, the conversion of cortisone to cortisol. Too much cortisol can lead to central obesity, and a particular variation in this gene has been associated with obesity and insulin resistance in children. Mutations in this gene and H6PD (hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)) are the cause of cortisone reductase deficiency. Alternate splicing results in multiple transcript variants encoding the same protein.
Category Type: Polyclonal Antibody
Research Areas: Cancer, Metabolism, Signal Transduction
Synonyms: HSD11B1, 11-DH, 11-beta-HSD1, CORTRD2, HDL, HSD11, HSD11B, HSD11L, SDR26C1
Reactivity: Mouse
Host: Rabbit
Isotype: IgG
Gene ID: 3290
Accession #:
Clonality:
Immunogen: Recombinant fusion protein of human HSD11B1 (NP_005516.1) .
Clone #:
Conjugation: Unconjugated
Swissprot: P28845
Santa Cruz:
Calculated MW: 32 kDa
Observed MW: 32 kDa
Concentration: 1 mg/mL
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Purification method: Affinity purification
Application: WB
Dilution: WB 1:500-1:2000
Storage: Store at -20°C. Avoid freeze / thaw cycles.
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