HTRA3 Polyclonal Antibody | G-AB-01563

HTRA3 Polyclonal Antibody | G-AB-01563 | Gentaur Antibodies

Overview: HtrA3, also known as PRSP (pregnancy-related serine protease) , is a 453 amino acid secreted protein that contains one PDZ domain, one Kazal-like domain and one IGFBP N-terminal domain. Widely expressed with particularly high expression in ovary, heart, placenta and bladder, HtrA3 functions as a probable serine protease that is thought to play an important role in placental development. HtrA3 is downregulated in ovarian tumors, suggesting an alternative role in tumor suppression. HtrA3 exists as two alternatively spliced isoforms, designated short and long. The gene encoding HtrA3 maps to human chromosome 4, which encodes nearly 6% of the human genome and has the largest gene deserts (regions of the genome with no protein encoding genes) of all of the human chromosomes.

Category Type: Polyclonal Antibody

Research Areas: Signal Transduction

Synonyms: High temperature requirement factor A3, High-temperature requirement factor A3, HtrA serine peptidase 3, HTRA3, HTRA3, Pregnancy related serine protease, Pregnancy-related serine protease, Probable serine protease HTRA3, PRSP, Serine protease HTRA3, Tasp

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID:

Accession #: NP_444272

Clonality: Polyclonal

Immunogen: Synthetic peptide of human HTRA3

Clone #:

Conjugation: Unconjugated

Swissprot: P83110

Santa Cruz: sc-79531/sc-79532/sc-130781

Calculated MW:

Observed MW:

Concentration: 0.2 mg/mL

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification method: Affinity purification

Application: IHC, ELISA

Dilution: IHC 1:50-1:200

Storage: Store at -20°C. Avoid freeze / thaw cycles.

HTRA3 Polyclonal Antibody DataSheet