HYAL2 Polyclonal Antibody | G-AB-01058

HYAL2 Polyclonal Antibody | G-AB-01058 | Gentaur Antibodies

Overview: This gene encodes a weak acid-active hyaluronidase. The encoded protein is similar in structure to other more active hyaluronidases. Hyaluronidases degrade hyaluronan, one of the major glycosaminoglycans of the extracellular matrix. Hyaluronan and fragments of hyaluronan are thought to be involved in cell proliferation, migration and differentiation. Although it was previously thought to be a lysosomal hyaluronidase that is active at a pH below 4, the encoded protein is likely a GPI-anchored cell surface protein. This hyaluronidase serves as a receptor for the oncogenic virus Jaagsiekte sheep retrovirus. The gene is one of several related genes in a region of chromosome 3p21.3 associated with tumor suppression. This gene encodes two alternatively spliced transcript variants which differ only in the 5' UTR.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Signal Transduction

Synonyms: Hyal 2, Hyal-2, Hyal2, HYAL2, Hyaluronidase 2, Hyaluronidase 2 Precursor, Hyaluronidase-2, Hyaluronoglucosaminidase 2, Hyaluronoglucosaminidase-2, LUCA 2, LUCA-2, LUCA2, Lung carcinoma protein 2, lysosomal hyaluronidase, PH 20 homolog, PH-20 homolog, PH20 homolog

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID:

Accession #: BC000692

Clonality: Polyclonal

Immunogen: Recombinant protein of human HYAL2

Clone #:

Conjugation: Unconjugated

Swissprot: Q12891

Santa Cruz: sc-99022

Calculated MW:

Observed MW:

Concentration: 0.6 mg/mL

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification method: Affinity purification

Application: IHC, ELISA

Dilution: IHC 1:100-1:300

Storage: Store at -20°C. Avoid freeze / thaw cycles.

HYAL2 Polyclonal Antibody DataSheet