IDH2 Polyclonal Antibody | G-AB-11549

IDH2 Polyclonal Antibody | G-AB-11549 | Gentaur Antibodies

Overview: Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD (+) as the electron acceptor and the other NADP (+) . Five isocitrate dehydrogenases have been reported: three NAD (+) -dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP (+) -dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. Each NADP (+) -dependent isozyme is a homodimer. The protein encoded by this gene is the NADP (+) -dependent isocitrate dehydrogenase found in the mitochondria. It plays a role in intermediary metabolism and energy production. This protein may tightly associate or interact with the pyruvate dehydrogenase complex. Alternative splicing results in multiple transcript variants.

Category Type: Polyclonal Antibody

Research Areas: Cancer, Metabolism, Signal Transduction

Synonyms: IDH2, D2HGA2, ICD-M, IDH, IDHM, IDP, IDPM, mNADP-IDH

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID: 3418

Accession #:

Clonality:

Immunogen: Recombinant fusion protein of human IDH2 (NP_002159.2) .

Clone #:

Conjugation: Unconjugated

Swissprot: P48735

Santa Cruz:

Calculated MW:

Observed MW:

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: IHC, IF

Dilution: IHC 1:50-1:200 IF 1:20-1:50

Storage: Store at -20°C. Avoid freeze / thaw cycles.

IDH2 Polyclonal Antibody DataSheet