IFI35 Polyclonal Antibody | G-AB-09402

IFI35 Polyclonal Antibody | G-AB-09402 | Gentaur Antibodies

Overview: The Interferon family of proteins are able to alter the expression of a variety of target genes, thereby controlling various events within the cell. IFI-35 (Interferon-induced 35 kDa protein) , also known as IFP35, is a 286 amino acid interferon-induced protein. Localized to the nucleus and expressed in macrophages, fibroblasts and epithelial cells, IFI-35 is a leucine zipper protein that can form homodimers, but, unlike most leucine zipper proteins, cannot bind DNA. Upon induction by IFN-α, IFI-35 associates with Nmi (N-Myc-interacting protein) , resulting in the formation of a high molecular weight complex that is thought to play a role in IFN-α signaling and cellular responses. Once complexed with Nmi, IFI-35 is unable to be degraded by the proteasome, suggesting that IFI-35 is protected from degradation only when needed by IFN-α. Two isoforms of IFI-35 exist due to alternative splicing events.

Category Type: Polyclonal Antibody

Research Areas: Cell Biology

Synonyms: IFI35, IFP35

Reactivity: Human, Mouse

Host: Rabbit

Isotype: IgG

Gene ID: 3430

Accession #:

Clonality:

Immunogen: Recombinant fusion protein of human IFI35 (NP_005524.2) .

Clone #:

Conjugation: Unconjugated

Swissprot: P80217

Santa Cruz:

Calculated MW: 31 kDa

Observed MW: 35 kDa

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: WB

Dilution: WB 1:500-1:2000

Storage: Store at -20°C. Avoid freeze / thaw cycles.

IFI35 Polyclonal Antibody DataSheet