IFT57 Polyclonal Antibody | G-AB-08760
Gentaur Antibodies
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Gentaur Antibodies
IFT57 Polyclonal Antibody | G-AB-08760
- SKU:
- G-AB-08760
- Availability:
- 3 to 5 Working Days
- Host:
- Rabbit
- Reactivity:
- Human, Mouse
IFT57 Polyclonal Antibody | G-AB-08760 | Gentaur Antibodies
Overview: Required for the formation of cilia. Plays an indirect role in sonic hedgehog signaling, cilia being required for all activity of the hedgehog pathway (By similarity) . Has pro-apoptotic function via its interaction with HIP1, leading to recruit caspase-8 (CASP8) and trigger apoptosis. Has the ability to bind DNA sequence motif 5'-AAAGACATG-3' present in the promoter of caspase genes such as CASP1, CASP8 and CASP10, suggesting that it may act as a transcription regulator; however the relevance of such function remains unclear.
Category Type: Polyclonal Antibody
Research Areas: Cancer, Neuroscience
Synonyms: IFT57, ESRRBL1, HIPPI, MHS4R2
Reactivity: Human, Mouse
Host: Rabbit
Isotype: IgG
Gene ID: 55081
Accession #:
Clonality:
Immunogen: Recombinant fusion protein of human IFT57 (NP_060480.1) .
Clone #:
Conjugation: Unconjugated
Swissprot: Q9NWB7
Santa Cruz:
Calculated MW:
Observed MW:
Concentration: 1 mg/mL
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Purification method: Affinity purification
Application: IHC
Dilution: IHC 1:50-1:200
Storage: Store at -20°C. Avoid freeze / thaw cycles.
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