IGF2R Polyclonal Antibody | G-AB-08015

IGF2R Polyclonal Antibody | G-AB-08015 | Gentaur Antibodies

Overview: This gene encodes a receptor for both insulin-like growth factor 2 and mannose 6-phosphate. The binding sites for each ligand are located on different segments of the protein. This receptor has various functions, including in the intracellular trafficking of lysosomal enzymes, the activation of transforming growth factor beta, and the degradation of insulin-like growth factor 2. Mutation or loss of heterozygosity of this gene has been association with risk of hepatocellular carcinoma. The orthologous mouse gene is imprinted and shows exclusive expression from the maternal allele; however, imprinting of the human gene may be polymorphic, as only a minority of individuals showed biased expression from the maternal allele (PMID:8267611) .

Category Type: Polyclonal Antibody

Research Areas: Cancer, Immunology, Signal Transduction, Tags & Cell Markers

Synonyms: IGF2R, CD222, CI-M6PR, CIMPR, M6P-R, M6P/IGF2R, MPR 300, MPR1, MPR300, MPRI

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Gene ID: 3482

Accession #:

Clonality:

Immunogen: Recombinant fusion protein of human IGF2R (NP_000867.2) .

Clone #:

Conjugation: Unconjugated

Swissprot: P11717

Santa Cruz:

Calculated MW:

Observed MW:

Concentration: 1 mg/mL

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification method: Affinity purification

Application: IHC, IF

Dilution: IHC 1:50-1:200 IF 1:50-1:200

Storage: Store at -20°C. Avoid freeze / thaw cycles.

IGF2R Polyclonal Antibody DataSheet